Resveratrol induces DNA damage-mediated cancer cell senescence through the DLC1–DYRK1A

Resveratrol induces DNA damage-mediated cancer cell senescence through the DLC1–DYRK1A–EGFR axis

Published:2023 Issue:3 Volume:14 Page:1484-1497
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Ma Fengqiu¹^ORCID,Ma Yan¹,Liu Keke¹,Gao Junying¹,Li Shasha¹,Sun Xiaowen¹,Li Guorong¹^ORCID

Affiliation:

1. Shandong Provincial Key Laboratory of Animal Resistant Biology, School of Life Sciences, Shandong Normal University, Jinan, 250014, Shandong, China

Abstract

Schematic representation of resveratrol inducing DNA damage-mediated cancer cell senescence through the DLC1–DYRK1A–EGFR axis.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2023/FO/D2FO01188C

Reference54 articles.

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5. Downregulation of the potential suppressor gene IGFBP-rP1 in human breast cancer is associated with inactivation of the retinoblastoma protein, cyclin E overexpression and increased proliferation in estrogen receptor negative tumors

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