Doxorubicin and PD-L1 siRNA co-delivery with stem cell membrane-coated polydopamine nanoparticles for the targeted chemoimmunotherapy of PCa bone metastases-Reference-Cited by-同舟云学术

Doxorubicin and PD-L1 siRNA co-delivery with stem cell membrane-coated polydopamine nanoparticles for the targeted chemoimmunotherapy of PCa bone metastases

Published:2021 Issue: Volume: Page:
ISSN:2040-3364
Container-title:Nanoscale
language:en
Short-container-title:Nanoscale

Author:

Mu Xupeng¹²³⁴⁵^ORCID,Zhang Meng¹²³⁴⁵,Wei Anhui⁶³⁴⁵,Yin Fei⁷²³⁴⁵,Wang Yan⁸²³⁴⁵,Hu Kebang⁹¹⁰⁴⁵,Jiang Jinlan¹²³⁴⁵^ORCID

Affiliation:

1. Scientific Research Center

2. China-Japan Union Hospital

3. Jilin University

4. Changchun

5. China

6. College of Pharmacy

7. Department of Orthopedics

8. Department of Hepatobiliary surgery

9. Department of Urology

10. The First Hospital of Jilin University

Abstract

Polydopamine nanoparticles camouflaged with stem cell membranes could effectively target tumor sites and showed excellent performance in synergistic chemoimmunotherapy for PCa bone metastases.

Funder

Jilin Scientific and Technological Development Program

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

Link

http://pubs.rsc.org/en/content/articlepdf/2021/NR/D0NR08024A

Reference22 articles.

1. Elements of cancer immunity and the cancer–immune set point

2. Suppression of Exosomal PD-L1 Induces Systemic Anti-tumor Immunity and Memory

3. PD-1 expression by tumour-associated macrophages inhibits phagocytosis and tumour immunity