An attempt to prepare sulfonyl analogues of fotemustine: unexpected rearrangement to sulfamate during nitrosation step-Reference-Cited by-同舟云学术

An attempt to prepare sulfonyl analogues of fotemustine: unexpected rearrangement to sulfamate during nitrosation step

Published:2023 Issue:50 Volume:13 Page:35741-35754
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Aouf Zineb¹^ORCID,Boughaba Sara¹²,Sayad Rayene¹,Lebreton Jacques³,Mathe-Allainmat Monique³^ORCID,Aouf Nour-Eddine¹

Affiliation:

1. Laboratory of Applied Organic Chemistry, Bioorganic Chemistry Group, Sciences Faculty, Chemistry Department, Badji Mokhtar-Annaba University, Box 12, Annaba 23000, Algeria

2. Higher National School of Forests, Khenchela, Algeria

3. Nantes Université, CNRS, CEISAM, UMR 6230, Nantes F-44000, France

Abstract

A flexible strategy to access to dialkyl (((N-(2-chloroethyl)-N-sulfamoyl) amino) arylmethyl) phosphonates, as sulfonamidophosphonates precursors of Fotemustine analogues was developed. The last nitrosation step proceeded as a rearrangement to the non expected sulfonate analogues.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/RA/D3RA07001H

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