The role of IP3R-SOCCs in Cr(vi)-induced cytosolic Ca2+ overload and apoptosis in L-02 hepatocytes
Author:
Affiliation:
1. Department of Radiology
2. The Third Xiangya Hospital
3. Central South University
4. Changsha 410013
5. PR China
6. Department of Health Toxicology
7. Xiangya School of Public Health
8. Changsha 410078
Abstract
Heavy metals such as hexavalent chromium [Cr(vi)] could induce Ca2+ overload and subsequently hepatocyte injury, and even apoptotic cell death, but the source of the increased cytosolic-free Ca2+ is still unclear.
Funder
National Natural Science Foundation of China
Publisher
Oxford University Press (OUP)
Subject
Health, Toxicology and Mutagenesis,Toxicology
Link
http://pubs.rsc.org/en/content/articlepdf/2018/TX/C8TX00029H
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