Catalytic enantioselective synthesis of carbocyclic and heterocyclic spiranes via a decarboxylative aldol cyclization-Reference-Cited by-同舟云学术

Catalytic enantioselective synthesis of carbocyclic and heterocyclic spiranes via a decarboxylative aldol cyclization

Published:2020 Issue:28 Volume:11 Page:7390-7395
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Inanaga Kazato¹²³⁴,Wollenburg Marco¹²³⁴,Bachman Shoshana¹²³⁴,Hafeman Nicholas J.¹²³⁴^ORCID,Stoltz Brian M.¹²³⁴^ORCID

Affiliation:

1. Warren and Katharine Schlinger Laboratory for Chemistry and Chemical Engineering

2. California Institute of Technology

3. Pasadena

4. USA

Abstract

The synthesis of a variety of enantioenriched 1,3-diketospiranes from the corresponding racemic allyl β-ketoesters via an interrupted asymmetric allylic alkylation is disclosed.

Funder

National Institute of General Medical Sciences

Astellas Pharma US

Amgen

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/SC/D0SC02366C

Reference63 articles.

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