Synthesis and anticancer properties of phenyl benzoate derivatives possessing a terminal hydroxyl group

Author:

Fukushi Yukako1234,Yoshino Hironori564,Ishikawa Junya564,Sagisaka Masanobu1234,Kashiwakura Ikuo564,Yoshizawa Atsushi1234

Affiliation:

1. Department of Frontier Materials Chemistry

2. Graduate School of Science and Technology

3. Hirosaki University

4. Hirosaki, Japan

5. Department of Radiological Life Sciences

6. Hirosaki University Graduate School of Health Sciences

Abstract

Liquid-crystalline molecules organize into a spherical particle to penetrate the cell membrane in A549 lung cancer cells and the molecules interact with the nucleus via the hydroxyl and ester groups to induce cell death.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

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