Self-assembling prodrugs
Author:
Affiliation:
1. Department of Oncology
2. The First Affiliated Hospital of Zhengzhou University
3. Zhengzhou 450052
4. China
5. Department of Chemical and Biomolecular Engineering
6. The Johns Hopkins University
7. Baltimore
8. USA
Abstract
Covalent modification of therapeutic compounds is a clinically proven strategy to devise prodrugs with enhanced treatment efficacies. Self-assembly of prodrugs expands the functional space of conventional prodrug design, providing a possible pathway to more effective therapies.
Funder
National Cancer Institute
Division of Materials Research
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2017/CS/C7CS00521K
Reference232 articles.
1. Chemical Aspects of Selective Toxicity
2. Prodrugs: design and clinical applications
3. Design of Ester Prodrugs to Enhance Oral Absorption of Poorly Permeable Compounds: Challenges to the Discovery Scientist
4. Prodrug strategies to overcome poor water solubility
5. Prodrugs for Amines
Cited by 296 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Recent advances in polysulfide-based prodrug nanomedicines for cancer therapy;Coordination Chemistry Reviews;2024-11
2. Research progress in tumor therapy of carrier-free nanodrug;Biomedicine & Pharmacotherapy;2024-09
3. Locally unlocks prodrugs by radiopharmaceutical in tumor for cancer therapy;Science Bulletin;2024-09
4. Peptide-Based Biomimetic Condensates via Liquid–Liquid Phase Separation as Biomedical Delivery Vehicles;Biomacromolecules;2024-08-23
5. In Vivo Self-Sorting of Peptides via In Situ Assembly Evolution;Journal of the American Chemical Society;2024-08-14
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3