Iron-catalyzed [3 + 2]-cycloaddition of in situ generated N-ylides with alkynes or olefins: access to multi-substituted/polycyclic pyrrole derivatives-Reference-Cited by-同舟云学术

Iron-catalyzed [3 + 2]-cycloaddition of in situ generated N-ylides with alkynes or olefins: access to multi-substituted/polycyclic pyrrole derivatives

Published:2020 Issue:3 Volume:18 Page:409-414
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Zhou Kai¹²³⁴⁵^ORCID,Bao Ming¹²³⁴⁵,Huang Jingjing¹²³⁴⁵,Kang Zhenghui¹²³⁴⁵^ORCID,Xu Xinfang¹²³⁴⁵^ORCID,Hu Wenhao¹²³⁴⁵,Qian Yu¹²³⁴⁵^ORCID

Affiliation:

1. Guangdong Provincial Key Laboratory of Chiral Molecule and Drug Discovery

2. School of Pharmaceutical Sciences

3. Sun Yat-sen University

4. Guangzhou 510006

5. China

Abstract

An iron-catalyzed three-component reaction of benzimidazoles with diazoacetates and electron-deficient alkynes or alkenes that delivers multi-substituted pyrroles, pyrrolo[1,2-a]benzimidazoles and pyrrolo[1,2-a] quinoxalinones has been reported.

Funder

National Natural Science Foundation of China

National Postdoctoral Program for Innovative Talents

Guangdong Province Introduction of Innovative R&D Team

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/OB/C9OB02571E

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1. Pro-aromatic and anti-aromatic π-conjugated molecules: an irresistible wish to be diradicals