Synthesis and biology of cyclic imine toxins, an emerging class of potent, globally distributed marine toxins

Author:

Stivala Craig E.1234,Benoit Evelyne56789,Aráoz Rómulo56789,Servent Denis1011121314,Novikov Alexei115164,Molgó Jordi56789,Zakarian Armen1718194

Affiliation:

1. Department of Chemistry

2. Stanford University

3. Stanford

4. USA

5. Institut de Neurobiologie Alfred Fessard

6. FRC2118

7. Laboratoire de Neurobiologie et Developpement

8. UPR-3294

9. Centre National de la Recherche Scientifique

10. Service d'Ingenierie Moleculaire des Proteines

11. Laboratoire de Toxinologie Moleculaire et Biotechnologies

12. Commissariat a l'Energie Atomique

13. F-91191 Gif-sur-Yvette

14. France

15. University of North Dakota

16. Grand Forks

17. Department of Chemistry and Biochemistry

18. University of California

19. Santa Barbara

Abstract

This review provides an full account of recent progress in discovery, synthesis, biology, and toxicology of a new and fascinating class of toxins known as Cyclic Imine (CI) toxins.

Funder

National Institute of General Medical Sciences

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Reference151 articles.

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4. T. Aune , Risk Assessment of Marine Toxins, in Seafood and Freshwater Toxins, ed. L. Botana, Taylor & Francis Group, LLC, 2nd edn, 2008, pp. 3–20

5. Gymnodimine, a new marine toxin of unprecedented structure isolated from New Zealand oysters and the dinoflagellate, Gymnodinium sp.

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