Furan-2-carbaldehydes as C1 building blocks for the synthesis of quinazolin-4(3H)-ones via ligand-free photocatalytic C

Furan-2-carbaldehydes as C1 building blocks for the synthesis of quinazolin-4(3H)-ones via ligand-free photocatalytic C–C bond cleavage

Published:2018 Issue:11 Volume:20 Page:2449-2454
ISSN:1463-9262
Container-title:Green Chemistry
language:en
Short-container-title:Green Chem.

Author:

Yu Wenjia¹²³⁴⁵,Zhang Xianwei⁵⁶⁷⁴,Qin Bingjie⁵⁶⁷⁴,Wang Qiyang¹²³⁴⁵,Ren Xuhong¹²³⁴,He Xinhua⁵⁶⁷⁴⁸^ORCID

Affiliation:

1. The Key Laboratory of Structure-Based Drug Design and Discovery

2. Shenyang Pharmaceutical University

3. Shenyang 110016

4. China

5. State Key Laboratory of Toxicology and Medical Countermeasures

6. Beijing Institute of Pharmacology and Toxicology

7. Beijing 100850

8. National Center of Biomedical Analysis

Abstract

Simple and inexpensive: The biomass-derived chemicals furan-2-carbaldehydes are efficient green C1 building blocks for the synthesis of biologically interesting quinazolin-4(3H)-ones via ligand-free photocatalytic C–C bond cleavage.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Beijing Municipality

Publisher

Royal Society of Chemistry (RSC)

Subject

Pollution,Environmental Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/GC/C8GC00079D

Reference72 articles.

1. Antihypertensive 2-amino-4(3H)-quinazolinones

2. Pharmacological Studies on Quaternized 4(3H)-Quinazolinones

3. Pharmacological Properties of 3-Amino-5,6,7,8-tetrahydro-2-{4-[4-(quinolin-2-yl)piperazin-1-yl]butyl}quinazolin-4(3H)-one (TZB-30878), a Novel Therapeutic Agent for Diarrhea-Predominant Irritable Bowel Syndrome (IBS) and Its Effects on an Experimental IBS Model

4. A convenient palladium-catalyzed carbonylative synthesis of 4(3H)-quinazolinones from 2-bromoformanilides and organo nitros with Mo(CO)6 as a multiple promoter

5. Pd/C as an efficient heterogeneous catalyst for carbonylative four-component synthesis of 4(3H)-quinazolinones

Cited by 15 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Electrochemical oxidative decarboxylative of α-oxocarboxylic acids towards the synthesis of quinazolines and quinazolinones;RSC Advances;2024

2. Divergent Synthesis of Quinolines: Exploiting the Duality of Free Radicals;Organic Letters;2023-12-11

3. Metal‐Free, Photoredox‐Catalyzed Synthesis of Quinazolin‐4(3H)‐ones and Benzo[4,5]imidazo[1,2‐c]quinazolines Using Trialkylamines as Alkyl Synthon;European Journal of Organic Chemistry;2023-02-24

4. DMSO as C1 Source under Metal‐ and Oxidant‐free Conditions: NH ₄ SCN‐mediated Synthesis of Quinazolinone and Dihydroquinazolin‐4(1H)‐one Derivatives;Asian Journal of Organic Chemistry;2022-07-06

5. Design of Photosensitive Cobalt Complex Intermediates and Their Application in the Green Syntheses of Molecules Containing the Quinazolin-4(3H)-imine Scaffold;The Journal of Organic Chemistry;2022-06-16