Lignans and [11]-chaetoglobosins from <i>Pseudeurotium bakeri</i> and their immunosuppressive activity-Reference-Cited by-同舟云学术

Lignans and [11]-chaetoglobosins from Pseudeurotium bakeri and their immunosuppressive activity

Published:2024 Issue:11 Volume:22 Page:2271-2278
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Duan Fangfang¹²,Qin Chunlun¹,Sang Zihuan²,Wei Xiaoyi²^ORCID,Ruan Hanli¹^ORCID

Affiliation:

1. School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, Wuhan 430030, People's Republic of China

2. Key Laboratory of South China Agricultural Plant Molecular Analysis and Genetic Improvement, Guangdong Provincial Key Laboratory of Applied Botany, South China Botanical Garden, Chinese Academy of Sciences, Guangzhou 510650, People's Republic of China

Abstract

Two lignans (1–2) and four [11]-chaetoglobosins (3–6) were obtained from Pseudeurotium bakeri P1-1-1. 2 and 3 exhibited significant immunosuppressive effects on T/B cell proliferation and dose-dependent induction of apoptosis in activated T cells.

Funder

Major Research Plan

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/OB/D3OB02109B

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