Tuning the drug multimodal release through a co-assembly strategy based on magnetic gels

Author:

Veloso Sérgio R. S.1ORCID,Tiryaki Ecem2,Spuch Carlos3,Hilliou Loic4,Amorim C. O.5ORCID,Amaral V. S.5,Coutinho Paulo J. G.1ORCID,Ferreira Paula M. T.6ORCID,Salgueiriño Verónica27ORCID,Correa-Duarte Miguel A.7ORCID,Castanheira Elisabete M. S.1ORCID

Affiliation:

1. Physics Centre of Minho and Porto Universities (CF-UM-UP) and LaPMET (Laboratory of Physics for Materials and Emergent Technologies), University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal

2. Departamento de Física Aplicada, Universidade de Vigo, 36310 Vigo, Spain

3. Translational Neuroscience Research Group, Galicia Sur Health Research Institute, CIBERSAM, Hospital Álvaro Cunqueiro, Bloque Técnico, Planta 2, Sala de Investigación, Estrada Clara Campoamor, 341, 36212 Vigo, Spain

4. Institute for Polymers and Composites, Department of Polymer Engineering, University of Minho, Campus de Azurém, 4800-058 Guimarães, Portugal

5. Physics Department and CICECO, University of Aveiro, Campus de Santiago, 3810-193 Aveiro, Portugal

6. Centro de Química (CQUM), University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal

7. CINBIO, Universidad de Vigo, 36310 Vigo, Spain

Abstract

Co-assembly of (di)phenylalanine-functionalized magnetic nanoparticles and liposomes with supramolecular peptide-based hydrogels for tunability of gel's properties, and modulation of both passive and active doxorubicin release.

Funder

Ministerio de Economía y Competitividad

Xunta de Galicia

Fundação para a Ciência e a Tecnologia

European Regional Development Fund

Programa Operacional Temático Factores de Competitividade

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

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