Redox chemistry-enabled stepwise surface dual nanoparticle engineering of 2D MXenes for tumor-sensitive T1 and T2 MRI-guided photonic breast-cancer hyperthermia in the NIR-II biowindow

Author:

Liu Zhuang1,Zhao Menglong2,Yu Luodan3,Peng Weijun1,Chen Yu3ORCID,Zhang Shengjian1

Affiliation:

1. Department of Radiology, Fudan University Shanghai Cancer Center; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, 200032, P. R. China

2. Department of Radiology, Zhongshan Hospital, Fudan University and Shanghai Institute of Medical Imaging, Shanghai, 200032, P. R. China

3. Materdicine Lab, School of Life Sciences, Shanghai University, Shanghai, 200444, P.R. China

Abstract

The 2D Nb2C MXene-based tumor microenvironment (TME) stimuli-responsive theranostic nanoplatform has been successfully demonstrated for dual-modality T1&T2 MR imaging-guided breast-cancer photothermal ablation.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

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