Catalyst free, C-3 functionalization of imidazo[1,2-a]pyridines to rapidly access new chemical space for drug discovery efforts-Reference-Cited by-同舟云学术

Catalyst free, C-3 functionalization of imidazo[1,2-a]pyridines to rapidly access new chemical space for drug discovery efforts

Published:2018 Issue:92 Volume:54 Page:12954-12957
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Gunaganti Naresh¹²³⁴^ORCID,Kharbanda Anupreet¹²³⁴,Lakkaniga Naga Rajiv¹²³⁴,Zhang Lingtian¹²³⁴,Cooper Rose¹²³⁴,Li Hong-yu¹²³⁴,Frett Brendan¹²³⁴^ORCID

Affiliation:

1. Department of Pharmaceutical Sciences

2. University of Arkansas for Medical Sciences

3. Little Rock

4. USA

Abstract

Development of a multicomponent reaction to functionalize the C-3 position of imidazo[1,2-a]pyridines via a three component, decarboxylation protocol.

Funder

University of Arkansas for Medical Sciences

American Thyroid Association

National Cancer Institute

National Institute of General Medical Sciences

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2018/CC/C8CC07063F

Reference50 articles.

1. The Application of Multi-Component Reactions in Drug Discovery

2. Isocyanide-based multicomponent reactions in drug discovery

3. Copper(II) Catalyzed Expeditious Synthesis of Furoquinoxalines through a One-Pot Three-Component Coupling Strategy

4. BF3·OEt2-Mediated Tandem Annulation: A Strategy To Construct Functionalized Chromeno- and Pyrano-Fused Pyridines

5. Molecular Iodine Promoted Divergent Synthesis of Benzimidazoles, Benzothiazoles, and 2-Benzyl-3-phenyl-3,4-dihydro-2H-benzo[e][1,2,4]thiadiazines

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