Ag(<scp>i</scp>)-catalyzed cyclization of <i>o</i>-alkynylacetophenones facilitated through acetal formation: synthesis of C3-naphthyl indole derivatives-Reference-Cited by-同舟云学术

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Ag(i)-catalyzed cyclization of o-alkynylacetophenones facilitated through acetal formation: synthesis of C3-naphthyl indole derivatives

Published:2022 Issue:48 Volume:20 Page:9698-9702
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Ramesh Golla¹,Srivardhan Valmuri¹,Balamurugan Rengarajan¹^ORCID

Affiliation:

1. School of Chemistry, University of Hyderabab, Hyderabad-500046, India

Abstract

Synthesis of C3-naphthylindoles has been achieved from o-alkynylacetophenones under acetalization conditions using trimethyl orthoformate and AgOTf.

Funder

University of Hyderabad

Science and Engineering Research Board

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/OB/D2OB01873J

Reference42 articles.

1. Novel 3-Aryl Indoles as Progesterone Receptor Antagonists for Uterine Fibroids

2. Carbonic anhydrase inhibitors. The β-carbonic anhydrases from the fungal pathogens Cryptococcus neoformans and Candida albicans are strongly inhibited by substituted-phenyl-1H-indole-5-sulfonamides

3. Synthesis and biological evaluation of substituted 2-sulfonyl-phenyl-3-phenyl-indoles: a new series of selective COX-2 inhibitors

4. Discovery and SAR of indole-2-carboxylic acid benzylidene-hydrazides as a new series of potent apoptosis inducers using a cell-based HTS assay

5. Base-mediated sequential one-pot approach for the synthesis of 2,3-disubstituted indoles from 2-(tosylamino)aryl-substituted para-quinone methides

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