A novel approach for obtaining α,β-diaminophosphonates bearing structurally diverse side chains and their interactions with transition metal ions studied by ITC
Author:
Affiliation:
1. Faculty of Chemistry
2. University of Opole
3. 45-052 Opole
4. Poland
5. Public Higher Medical Professional School in Opole
6. 45-060 Opole
7. Department of Bioorganic Chemistry
8. Wrocław University of Science and Technology
9. 50-370 Wrocław
Abstract
A convenient and general reaction is presented for the preparation of diaminophosphonates further evaluated as chelators of metal ions.
Funder
Narodowe Centrum Nauki
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2020/RA/D0RA03764H
Reference46 articles.
1. Inhibition of aminopeptidases by aminophosphonates
2. Remarkable Potential of the α-Aminophosphonate/Phosphinate Structural Motif in Medicinal Chemistry
3. Tailoring of Integrin Ligands: Probing the Charge Capability of the Metal Ion-Dependent Adhesion Site
4. A structural insight into the P1 S1 binding mode of diaminoethylphosphonic and phosphinic acids, selective inhibitors of alanine aminopeptidases
5. Enantiomeric α,β-diaminoethylphosphonic acids as potent inhibitors of aminopeptidases—stereoselective synthesis and biological activity
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1. N-Functionalization of β-aminophosphonates: cytotoxic effects of the new derivatives;Organic & Biomolecular Chemistry;2024
2. Synthesis of α,β -diamino acid derivatives by acid-catalyzed Aza-Michael addition of N -phthalyldehydroalanine with different amine;Synthetic Communications;2023-12-03
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