A Turn-ON fluorometric biosensor based on ssDNA immobilized with a metal phenolic nanomaterial for the sequential detection of Pb(ii) and epirubicin cancer drug-Reference-Cited by-同舟云学术

A Turn-ON fluorometric biosensor based on ssDNA immobilized with a metal phenolic nanomaterial for the sequential detection of Pb(ii) and epirubicin cancer drug

Published:2021 Issue:20 Volume:11 Page:12361-12373
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Arunjegan A.¹²³,Rajaji P.¹²³,Sivanesan S.⁴⁵⁶⁷³^ORCID,Panneerselvam P.¹²³^ORCID

Affiliation:

1. Department of Chemistry

2. SRM Institute of Science and Technology

3. India

4. Department of Applied Science and Technology

5. A. C Technology

6. Anna University

7. Chennai

Abstract

In this paper, we propose a fluorescent biosensor for the sequential detection of Pb²⁺ ions and the cancer drug epirubicin (Epn) using the interactions between label-free guanine-rich ssDNA (LFGr-ssDNA), acridine orange (AO), and a metal–phenolic nanomaterial.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/RA/D1RA00939G

Reference41 articles.

1. Defining potential roles of Pb2+in neurotoxicity from a calciomics approach

2. An electrochemical aptasensor for lead ion detection based on catalytic hairpin assembly and porous carbon supported platinum as signal amplification

3. A Novel Polydopamine Grafted 3D MOF Nanocubes Mediated GR-5/GC DNAzyme Complex with Enhanced Fluorescence Emission Response toward Spontaneous Detection of Pb(II) and Ag(I) Ions

4. A new sensor consisting of Ag-MWCNT nanocomposite as the sensing element for electrochemical determination of Epirubicin

5. Mapping Genes that Contribute to Daunorubicin-Induced Cytotoxicity

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