Defluorinative [4 + 1] annulation of perfluoroalkyl N-mesylhydrazones with primary amines provides 5-fluoroalkyl 1,2,3-triazoles-Reference-Cited by-同舟云学术

Defluorinative [4 + 1] annulation of perfluoroalkyl N-mesylhydrazones with primary amines provides 5-fluoroalkyl 1,2,3-triazoles

Published:2021 Issue:20 Volume:23 Page:7976-7981
ISSN:1463-9262
Container-title:Green Chemistry
language:en
Short-container-title:Green Chem.

Author:

Ning Yongquan¹^ORCID,Wang Hongwei¹,Sivaguru Paramasivam¹^ORCID,Li Shuang¹,Zanoni Giuseppe²,Nolan Steven P.³,Bi Xihe¹⁴^ORCID

Affiliation:

1. Department of Chemistry, Northeast Normal University, Changchun 130024, China

2. Department of Chemistry, University of Pavia, Viale Taramelli 12, 27100 Pavia, Italy

3. Department of Chemistry and Sustainable Chemistry, Ghent University, 281 Krijgslaan S-3, 9000, Ghent, Belgium

4. State Key Laboratory of Elemento-Organic Chemistry, Nankai University, Tianjin 300071, China

Abstract

A novel azide-free approach for the synthesis of 5-perfluoroalkyl-1,2,3-triazoles via the [4 + 1] annulation of perfluoroalkyl N-mesylhydrazones (PFHZ-Ms) with primary amines was realized under mild conditions.

Funder

National Natural Science Foundation of China

Department of Science and Technology of Jilin Province

Fundamental Research Funds for the Central Universities

Universiteit Gent

Publisher

Royal Society of Chemistry (RSC)

Subject

Pollution,Environmental Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/GC/D1GC02749B

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