Dendrimer-PLGA based multifunctional immuno-nanocomposite mediated synchronous and tumor selective delivery of siRNA and cisplatin: potential in treatment of hepatocellular carcinoma-Reference-Cited by-同舟云学术

Dendrimer-PLGA based multifunctional immuno-nanocomposite mediated synchronous and tumor selective delivery of siRNA and cisplatin: potential in treatment of hepatocellular carcinoma

Published:2015 Issue:49 Volume:5 Page:39512-39531
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Sherwani Mohd. Asif¹²³⁴,Tufail Saba¹²³⁴,Khan Aijaz Ahmed⁵⁶⁷²³,Owais Mohammad¹²³⁴

Affiliation:

1. Interdisciplinary Biotechnology Unit

2. Aligarh Muslim University

3. Aligarh

4. India

5. Department of Anatomy

6. Jawaharlal Nehru Medical College

7. Faculty of Medicine

Abstract

The in-house synthesized PLK-1 siRNA and cisplatin loaded innovative dendrimer-PLGA immuno-nanocomposite bears the capacity of delivering both the cargos simultaneously to the same liver cancer cell in a targeted manner.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/RA/C5RA03651H

Reference63 articles.

1. pH-responsive complexes using prefunctionalized polymers for synchronous delivery of doxorubicin and siRNA to cancer cells

2. Knocking down barriers: advances in siRNA delivery

3. Enhancing tumor cell response to chemotherapy through nanoparticle-mediated codelivery of siRNA and cisplatin prodrug

4. Multimodal Nanodiamond Drug Delivery Carriers for Selective Targeting, Imaging, and Enhanced Chemotherapeutic Efficacy

5. Impact of Nanotechnology on Drug Delivery

Cited by 24 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Design, Synthesis and Evaluation of a Novel Teoptinib Derivative as an Effective Anti-hepatocellular Carcinoma Agent;Current Pharmaceutical Design;2024-08

2. Poly lactic-co-glycolic acid nanoparticles for anticancer therapy;Cancer Therapy;2024

3. Fabrication of epidermal growth factor functionalized polymeric poly(lactic-co-glycolic acid) nanoparticles loaded SN-38 and perfluorocarbon for treatment and care: investigation of antiproliferative effects and apoptosis in cervical cancer cells;Journal of Macromolecular Science, Part A;2023-08-14

4. Nanomaterials for Targeting Liver Disease: Research Progress and Future Perspectives;Nano Biomedicine and Engineering;2023-06

5. Fabrication of metformin and survivin siRNA encapsulated into polyethyleneimine-altered silk fibroin nanoparticles for the treatment of nasopharyngeal carcinoma;Process Biochemistry;2023-02