The synthesis of a series of adenosine A3 receptor agonists
Author:
Affiliation:
1. Cardiff School of Pharmacy and Pharmaceutical Sciences
2. Cardiff University
3. Cardiff
4. UK
5. The School of Chemistry
6. The University of Manchester
7. Manchester
8. Muscagen Limited
Abstract
A series of 1′-(6-aminopurin-9-yl)-1′-deoxy-N-methyl-β-d-ribofuranuronamides that were characterised by 2-dialkylamino-7-methyloxazolo[4,5-b]pyridin-5-ylmethyl substituents on N6 of interest for screening as selective adenosine A3 receptor agonists, have been synthesised.
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2016/OB/C6OB00244G
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5. A3 adenosine receptor: Homology modeling and 3D-QSAR studies
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