Visible light-induced halogen-atom transfer by N-heterocyclic carbene-ligated boryl radicals for diastereoselective C(sp<sup>3</sup>)–C(sp<sup>2</sup>) bond formation-Reference-Cited by-同舟云学术

Visible light-induced halogen-atom transfer by N-heterocyclic carbene-ligated boryl radicals for diastereoselective C(sp³)–C(sp²) bond formation

Published:2024 Issue: Volume: Page:
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Capaldo Luca¹²^ORCID,Wan Ting¹³,Mulder Robin¹,Djossou Jonas¹,Noël Timothy¹^ORCID

Affiliation:

1. Flow Chemistry Group, Van 't Hoff Institute for Molecular Sciences (HIMS), University of Amsterdam, Science Park 904, 1098 XH Amsterdam, The Netherlands

2. Department of Chemistry, SynCat Lab, Life Sciences and Environmental Sustainability, University of Parma, 43124 Parma, Italy

3. The Research Center of Chiral Drugs, Innovation Research Institute of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China

Abstract

In this work, we report the synthesis of vinyl chlorides from chloroalkynes via ligated boryl radicals-mediated XAT under visible light. This study introduces the first protocol using XAT to establish a C(sp3)–C(sp2) bond through radical addition.

Funder

H2020 European Research Council

Dipartimenti di Eccellenza

China Scholarship Council

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/SC/D4SC02962C

Reference43 articles.

1. Radicals in Action: A Festival of Radical Transformations

2. Catalysis of Radical Reactions: A Radical Chemistry Perspective

3. Electrocatalysis as an enabling technology for organic synthesis

4. Generation of Alkyl Radicals: From the Tyranny of Tin to the Photon Democracy

5. Applications of Halogen-Atom Transfer (XAT) for the Generation of Carbon Radicals in Synthetic Photochemistry and Photocatalysis