Engineering the biosynthesis of fungal nonribosomal peptides

Author:

Zhang Liwen1ORCID,Wang Chen1ORCID,Chen Kang1,Zhong Weimao2ORCID,Xu Yuquan1ORCID,Molnár István23ORCID

Affiliation:

1. Biotechnology Research Institute, The Chinese Academy of Agricultural Sciences, 12 Zhongguancun South Street, Beijing 100081, P. R. China

2. Southwest Center for Natural Products Research, University of Arizona, 250 E. Valencia Rd., Tucson, AZ 85706, USA

3. VTT Technical Research Centre of Finland, P.O. Box 1000, FI-02044 VTT, Espoo, Finland

Abstract

Fungal nonribosomal peptides (NRPs) and the related polyketide–nonribosomal peptide hybrid products (PK–NRPs) are a prolific source of bioactive compounds, some of which have been developed into essential drugs.

Funder

National Natural Science Foundation of China

National Institute of Food and Agriculture

Chinese Academy of Agricultural Sciences

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

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