Insertion of Pro-Hyp-Gly provides 2 kcal mol−1 stability but attenuates the specific assembly of ABC heterotrimeric collagen triple helices
Author:
Affiliation:
1. Department of Chemistry
2. National Taiwan University
3. Taipei 10617
4. Taiwan
5. Department of Academic Affairs and Instrument Service
6. and Institute of Biological Chemistry
7. Academia Sinica
8. Taipei 11529
Abstract
Collagen triple helices are stabilized by 2 kcal mol−1 upon inserting proline-hydroxyproline-glycine but attenuates the specific assembly of the ABC heterotrimer.
Funder
Ministry of Science and Technology, Taiwan
Academia Sinica
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2021/OB/D0OB02190C
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