A short GC rich DNA derived from microbial origin targets tubulin/microtubules and induces apoptotic death of cancer cells-Reference-Cited by-同舟云学术

A short GC rich DNA derived from microbial origin targets tubulin/microtubules and induces apoptotic death of cancer cells

Published:2015 Issue:60 Volume:51 Page:12024-12027
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Jana Batakrishna¹²³⁴,Sarkar Jayita¹²³⁴,Mondal Prasenjit⁵⁶⁷⁴,Barman Surajit¹²³⁴,Mohapatra Saswat⁵⁶⁷⁴,Bhunia Debmalya¹²³⁴,Pradhan Krishnangsu¹²³⁴,Saha Abhijit¹²³⁴,Adak Anindyasundar¹²³⁴,Ghosh Subhajit¹²³⁴,Ghosh Surajit¹²³⁴⁵

Affiliation:

1. Organic & Medicinal Chemistry Division

2. CSIR-Indian Institute of Chemical Biology

3. Kolkata-700032

4. India

5. Academy of Scientific and Innovative Research (AcSIR)

6. CSIR-Indian Institute of Chemical Biology Campus

7. Kolkata 700 032

Abstract

A short GC rich DNA interacts with tubulin/microtubules, activates p53 over expression and induces apoptotic death of human breast cancer (MCF-7) cells.

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2015/CC/C5CC03432A

Reference45 articles.

1. MICROTUBULE POLYMERIZATION DYNAMICS

2. Chromosome-Microtubule Interactions During Mitosis

3. Microtubules and signal transduction

4. Structural Insights into Microtubule Function

5. Microtubule-binding agents: a dynamic field of cancer therapeutics

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