Chemoenzymatic synthesis of glycopeptides bearing rare N-glycan sequences with or without bisecting GlcNAc-Reference-Cited by-同舟云学术

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Chemoenzymatic synthesis of glycopeptides bearing rare N-glycan sequences with or without bisecting GlcNAc

Published:2018 Issue:43 Volume:9 Page:8194-8206
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Yang Weizhun¹²³⁴,Ramadan Sherif¹²³⁴⁵^ORCID,Orwenyo Jared⁶⁷⁴,Kakeshpour Tayeb¹²³⁴,Diaz Thomas¹²³⁴,Eken Yigitcan¹²³⁴,Sanda Miloslav⁸⁹¹⁰⁴,Jackson James E.¹²³⁴,Wilson Angela K.¹²³⁴,Huang Xuefei¹²³⁴¹¹^ORCID

Affiliation:

1. Department of Chemistry

2. Michigan State University

3. East Lansing

4. USA

5. Chemistry Department

6. Department of Chemistry and Biochemistry

7. University of Maryland

8. Department of Oncology

9. Georgetown University

10. Washington DC 20057

11. Department of Biomedical Engineering

Abstract

A glycopeptide bearing a bisecting glucosamine, a rare N-glycan branch, and two Lewis^Xtrisaccharides was synthesized for the first time.

Funder

National Cancer Institute

National Science Foundation

National Institute of General Medical Sciences

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/SC/C8SC02457J

Reference54 articles.

1. Glycomics Hits the Big Time

2. Synthesis of post-translationally modified proteins

3. Post-translational modifications in the context of therapeutic proteins

4. The Impact of Glycosylation on the Biological Function and Structure of Human Immunoglobulins

5. Effect of glycosylation on protein folding: A close look at thermodynamic stabilization

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1. Encouraging Solution to the Problem of Synthesizing Protein α‐Thioester;Chinese Journal of Chemistry;2024-02-05

2. Recent advances in enzymatic and chemoenzymatic synthesis of N- and O-glycans;Current Opinion in Chemical Biology;2024-02

3. Divergent Enzymatic Assembly of a Comprehensive 64‐Membered IgG N‐Glycan Library for Functional Glycomics;Advanced Science;2023-08-26

4. Stereoselective synthesis of photoactivatable Man(β1,4)GlcNAc-based bioorthogonal probes;Tetrahedron Letters;2023-06

5. Profiling the Bisecting N-acetylglucosamine Modification in Amniotic Membrane via Mass Spectrometry;Genomics, Proteomics & Bioinformatics;2022-08

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