Intracellular label-free detection of mesenchymal stem cell metabolism within a perivascular niche-on-a-chip-Reference-Cited by-同舟云学术

Intracellular label-free detection of mesenchymal stem cell metabolism within a perivascular niche-on-a-chip

Published:2021 Issue:7 Volume:21 Page:1395-1408
ISSN:1473-0197
Container-title:Lab on a Chip
language:en
Short-container-title:Lab Chip

Author:

Perottoni Simone¹²³⁴⁵^ORCID,Neto Nuno G. B.⁶⁷⁸⁹¹⁰^ORCID,Di Nitto Cesare¹²³⁴⁵,Dmitriev Ruslan I.¹¹¹²¹³¹⁴¹⁵^ORCID,Raimondi Manuela Teresa¹²³⁴⁵^ORCID,Monaghan Michael G.⁶⁷⁸⁹¹⁰^ORCID

Affiliation:

1. Department of Chemistry

2. Materials and Chemical Engineering “Giulio Natta”

3. Politecnico di Milano

4. 32 – 20133 Milan

5. Italy

6. Department of Mechanical

7. Manufacturing and Biomedical Engineering

8. Trinity College Dublin

9. Dublin 2

10. Ireland

11. Tissue Engineering and Biomaterials Group

12. Department of Human Structure and Repair

13. Faculty of Medicine and Health Sciences

14. Ghent University

15. Ghent 9000

Abstract

The stem cell niche at the perivascular space plays a role in dictating the fate of stem cells within it. This study predicts in silico and models the perivascular space, in a miniaturised bioreactor, with non-invasive assessment of cell metabolism.

Funder

Trinity College Dublin

H2020 European Research Council

Ministry of Education, Universities and Research

National Centre for the Replacement, Refinement and Reduction of Animals in Research

Science Foundation Ireland

European Research Council

European Commission

European Space Agency

Publisher

Royal Society of Chemistry (RSC)

Subject