Lycopene prevents DEHP-induced testicular endoplasmic reticulum stress via regulating nuclear xenobiotic receptors and unfolded protein response in mice-Reference-Cited by-同舟云学术

Lycopene prevents DEHP-induced testicular endoplasmic reticulum stress via regulating nuclear xenobiotic receptors and unfolded protein response in mice

Published:2021 Issue:24 Volume:12 Page:12256-12264
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Zhao Yi¹,Cui Ling-Ge¹,Talukder Milton¹²,Cui Jia-Gen¹,Zhang Hao¹,Li Jin-Long¹³⁴^ORCID

Affiliation:

1. College of Veterinary Medicine, Northeast Agricultural University, Harbin, 150030, P. R. China

2. Department of Physiology and Pharmacology, Faculty of Animal Science and Veterinary Medicine, Patuakhali Science and Technology University, Bangladesh

3. Heilongjiang Key Laboratory for Laboratory Animals and Comparative Medicine, Northeast Agricultural University, Harbin, 150030, P. R. China

4. Key Laboratory of the Provincial Education Department of Heilongjiang for Common Animal Disease Prevention and Treatment, Northeast Agricultural University, Harbin, 150030, P. R. China

Abstract

The present study suggested that LYC prevents DEHP-induced ER stress in testis via regulating NXRs and UPRER. This study indicated that NXRs and UPRER might be a new strategy for the prevention of DEHP-induced testicular toxicity by LYC.

Funder

Natural Science Foundation of Heilongjiang Province

National Natural Science Foundation of China

Ministry of Finance

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2021/FO/D1FO02729H

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