Pd-catalyzed asymmetric allylic substitution cascade using α-(pyridin-1-yl)-acetamides formedin situas nucleophiles-Reference-Cited by-同舟云学术

Pd-catalyzed asymmetric allylic substitution cascade using α-(pyridin-1-yl)-acetamides formedin situas nucleophiles

Published:2019 Issue:6 Volume:10 Page:1767-1772
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Yao Kun¹²³⁴⁵,Yuan Qianjia⁶³⁴⁵,Qu Xingxin¹²³⁴⁵,Liu Yangang¹²³⁴⁵,Liu Delong¹²³⁴⁵^ORCID,Zhang Wanbin¹²³⁴⁵^ORCID

Affiliation:

1. Shanghai Key Laboratory for Molecular Engineering of Chiral Drugs

2. School of Pharmacy

3. Shanghai Jiao Tong University

4. Shanghai 200240

5. P. R. China

6. School of Chemistry and Chemical Engineering

Abstract

A Pd-catalyzed asymmetric allylic substitution cascade reaction, using α-(pyridin-1-yl)-acetamides (formedin situ) as nucleophiles, has been developed.

Funder

Shanghai Municipal Education Commission

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/SC/C8SC04626C

Reference71 articles.

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3. An overview of the synthetic routes to the best selling drugs containing 6-membered heterocycles

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