Dynamic 3D in vitro lung models: applications of inorganic nanoparticles for model development and characterization

Author:

Fallert Laura123,Urigoitia-Asua Ane134,Cipitria Amaia25ORCID,Jimenez de Aberasturi Dorleta156ORCID

Affiliation:

1. Department of Hybrid Biofunctional Materials, CIC biomaGUNE, Basque Research and Technology Alliance (BRTA), Paseo de Miramon 194, 20014 Donostia-San Sebastián, Spain

2. Group of Bioengineering in Regeneration and Cancer, Biogipuzkoa Health Research Institute, 20014 Donostia-San Sebastián, Spain

3. Department of Applied Chemistry, University of the Basque Country, 20018 Donostia-San Sebastián, Spain

4. POLYMAT, Basque Centre for Macromolecular Design and Engineering, 20018 Donostia-San Sebastián, Spain

5. Ikerbasque, Basque Foundation for Science, 48009 Bilbao, Spain

6. Centro de Investigación Biomédica en Red de Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN, ISCIII), 20014 Donostia-San Sebastián, Spain

Abstract

In this review, the authors elaborate on the most recent advances of lung in vitro models and inform on the potential of nanoparticles as a means to create dynamic models as well as nanoparticle-based characterization strategies.

Funder

Ministerio de Ciencia e Innovación

Eusko Jaurlaritza

Publisher

Royal Society of Chemistry (RSC)

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