The emergence of the C–H functionalization strategy in medicinal chemistry and drug discovery-Reference-Cited by-同舟云学术

The emergence of the C–H functionalization strategy in medicinal chemistry and drug discovery

Published:2021 Issue:83 Volume:57 Page:10842-10866
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Jana Ranjan¹^ORCID,Begam Hasina Mamataj¹,Dinda Enakshi²

Affiliation:

1. Organic and Medicinal Chemistry Division, CSIR-Indian Institute of Chemical Biology, 4 Raja S. C. Mullick Road, Kolkata-700032, India

2. Department of Chemistry and Environment, Heritage Institute of Technology, Kolkata-700107, India

Abstract

The application of representative C–H activation/functionalization reactions for drug synthesis, late-stage modification of pharmacophores, bioconjugation and representative case studies for accelerated drug discovery is highlighted.

Funder

Science and Engineering Research Board

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2021/CC/D1CC04083A

Reference281 articles.

1. The importance of greater speed in drug development for advanced malignancies

2. Computational Methods in Drug Discovery

3. Artificial intelligence in drug discovery and development

4. Organic synthesis provides opportunities to transform drug discovery

5. The role of the medicinal chemist in drug discovery — then and now

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