Polymeric Gd-DOTA amphiphiles form spherical and fibril-shaped nanoparticle MRI contrast agents-Reference-Cited by-同舟云学术

Polymeric Gd-DOTA amphiphiles form spherical and fibril-shaped nanoparticle MRI contrast agents

Published:2016 Issue:7 Volume:7 Page:4230-4236
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Randolph Lyndsay M.¹²³⁴,LeGuyader Clare L. M.¹²³⁴,Hahn Michael E.¹²³⁴⁵,Andolina Christopher M.⁶⁷⁸⁴,Patterson Joseph P.¹²³⁴,Mattrey Robert F.⁵²³⁴,Millstone Jill E.⁶⁷⁸⁴^ORCID,Botta Mauro⁹¹⁰¹¹¹²^ORCID,Scadeng Miriam⁵²³⁴,Gianneschi Nathan C.¹²³⁴

Affiliation:

1. Department of Chemistry and Biochemistry

2. University of California

3. San Diego

4. USA

5. Department of Radiology

6. Department of Chemistry

7. University of Pittsburgh

8. Pittsburgh

9. Dipartimento di Scienze e Innovazione Tecnologica

10. Università del Piemonte Orientale “A. Avogadro”

11. Alessandria

12. Italy

Abstract

A Gd³⁺-coordinated polymerizable analogue of the MRI contrast agent Gd-DOTA was used to prepare amphiphilic block copolymers, with hydrophilic blocks composed entirely of the polymerized contrast agent.

Funder

NIH Office of the Director

National Heart, Lung, and Blood Institute

National Institutes of Health

U.S. Department of Education

National Institute of Biomedical Imaging and Bioengineering

Alfred P. Sloan Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link