The regioselective annulation of <i>N</i>-methylpyridinium ylides with alkenes enabled by palladium catalysis: access to 3-unsubstituted indolizine derivatives-Reference-Cited by-同舟云学术

The regioselective annulation of N-methylpyridinium ylides with alkenes enabled by palladium catalysis: access to 3-unsubstituted indolizine derivatives

Published:2022 Issue:17 Volume:9 Page:4719-4725
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Gou Quan¹^ORCID,Zhu Qianhua¹,Deng Mengjiao¹,Li Weiwei¹,Ran Xing¹,Xie Jianfeng²,Huang Huisheng¹,Tan Xiaoping¹,Zhu Minghong³

Affiliation:

1. Chongqing Key Laboratory of Inorganic Special Functional Materials, School of Chemistry and Chemical Engineering, Yangtze Normal University, Chongqing, 408100, China

2. Department of Chongqing General Hospital, University of Chinese Academy of Sciences, Chongqing 400013, China

3. Fuling Hospital, Chongqing University, Chongqing, 408000, China

Abstract

The first catalytic protocol for the regioselective [3 + 2] annulation of N-methyl pyridinium ylides with alkenes to establish various valuable 3-unsubstituted indolizine derivatives is accomplished via palladium catalysis at the unactivated position.

Funder

Chongqing Municipal Education Commission

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/QO/D2QO00555G

Reference59 articles.

1. Organic synthesis provides opportunities to transform drug discovery

2. Fluorinated Pyrazoles: From Synthesis to Applications

3. Anticancer Properties of Lamellarins

4. Recent progress in synthesis and bioactivity studies of indolizines

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