Analysing the microenvironment of 2-p-toluidinylnaphthalene-6-sulfonate (TNS) in solvents and in different conformational states of proteins in relation to its fluorescence properties: a computational study
Author:
Affiliation:
1. Department of Biotechnology and Bioinformatics
2. School of Life Sciences
3. University of Hyderabad
4. Hyderabad – 500046
5. India
Abstract
TNS in aggregated form might show less fluorescence whereas monomeric or lower order aggregates positioned in hydrophobic crevices of a protein might enhance its fluorescence.
Funder
Council for Scientific and Industrial Research
Publisher
Royal Society of Chemistry (RSC)
Subject
Physical and Theoretical Chemistry,General Physics and Astronomy
Link
http://pubs.rsc.org/en/content/articlepdf/2017/CP/C7CP03951D
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3. J. R. Lakowicz , Principles of Fluorescence Spectroscopy, Springer, US, 2007
4. Single-Molecule Studies of Intrinsically Disordered Proteins
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