Discovery of new polycyclic polyprenylated acylphloroglucinols with diverse architectures as potent cyclooxygenase-2 inhibitors-Reference-Cited by-同舟云学术

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Discovery of new polycyclic polyprenylated acylphloroglucinols with diverse architectures as potent cyclooxygenase-2 inhibitors

Published:2020 Issue:11 Volume:7 Page:1349-1357
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Xie Shuangshuang¹²³⁴⁵,Qi Changxing¹²³⁴⁵,Duan Yulin¹²³⁴⁵,Xu Qianqian¹²³⁴⁵,Liu Yaping¹²³⁴⁵,Huang Yingying¹²³⁴⁵,Yin Xu⁶⁷⁸⁹¹⁰,Sun Weiguang¹²³⁴⁵,Zhou Yuan¹²³⁴⁵^ORCID,Zhang Yonghui¹²³⁴⁵^ORCID

Affiliation:

1. Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation

2. School of Pharmacy

3. Tongji Medical College

4. Huazhong University of Science and Technology

5. Wuhan 430030

6. Department of Natural Medicines

7. School of Pharmaceutical Sciences

8. Peking University Health Science Center

9. Beijing

10. People's Republic of China

Abstract

Cyclooxygenase-2 (COX-2) is a significant therapeutic target of chronic inflammatory diseases.

Funder

Changjiang Scholar Program of Chinese Ministry of Education

National Science Fund for Distinguished Young Scholars

National Natural Science Foundation of China

Tongji Medical College, Huazhong University of Science and Technology

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/QO/D0QO00259C

Reference15 articles.

1. Research Progress of Polycyclic Polyprenylated Acylphloroglucinols

2. Polycyclic Polyprenylated Acylphloroglucinols

3. Polycyclic Polyprenylated Derivatives from Hypericum uralum: Neuroprotective Effects and Antidepressant-like Activity of Uralodin A

4. Tricyclic Polyprenylated Acylphloroglucinols from St John’s Wort, Hypericum perforatum

5. Rapid Synthesis of Polyprenylated Acylphloroglucinol Analogs via Dearomative Conjunctive Allylic Annulation

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