Controlled release of lidocaine hydrochloride from polymerized drug-based deep-eutectic solvents
Author:
Affiliation:
1. Polymer & Biopolymer Research Group
2. Centro de Investigación y de Estudios Avanzados
3. Querétaro, Mexico
4. Department of Chemistry
5. Louisiana State University
6. Baton Rouge, USA
Abstract
This work takes advantage of the transformation of lidocaine hydrochloride into deep-eutectic solvents (DESs) – ionic liquid analogues – to incorporate polymerizable counterparts into DESs, such that polymer–drug complexes are synthesized by free-radical frontal polymerization without the use of a solvent.
Publisher
Royal Society of Chemistry (RSC)
Subject
General Materials Science,Biomedical Engineering,General Chemistry,General Medicine
Link
http://pubs.rsc.org/en/content/articlepdf/2014/TB/C4TB01407C
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