An anti-glioblastoma gold(<scp>i</scp>)–NHC complex distorts mitochondrial morphology and bioenergetics to induce tumor growth inhibition-Reference-Cited by-同舟云学术

An anti-glioblastoma gold(i)–NHC complex distorts mitochondrial morphology and bioenergetics to induce tumor growth inhibition

Published:2023 Issue:8 Volume:4 Page:592-599
ISSN:2633-0679
Container-title:RSC Chemical Biology
language:en
Short-container-title:RSC Chem. Biol.

Author:

Greif Charles E.¹,Mertens R. Tyler¹,Berger Gilles²³^ORCID,Parkin Sean¹^ORCID,Awuah Samuel G.¹⁴⁵^ORCID

Affiliation:

1. Department of Chemistry, University of Kentucky, Lexington, Kentucky 40506, USA

2. Harvey Cushing Neuro-Oncology Laboratories, Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA

3. Microbiology, Bioorganic & Macromolecular Chemistry, Faculté de Pharmacie, Université libre de Bruxelles (ULB), Boulevard du Triomphe, 1050 Brussels, Belgium

4. Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, Lexington, Kentucky 40536, USA

5. University of Kentucky Markey Cancer Center, University of Kentucky, Lexington, KY, 40536, USA

Abstract

A new gold(i)-based therapeutic strategy to treat glioblastoma multiforme (GBM).

Funder

National Institutes of Health

Publisher

Royal Society of Chemistry (RSC)

Subject

Biochemistry, Genetics and Molecular Biology (miscellaneous),Molecular Biology,Biochemistry,Chemistry (miscellaneous)

Link

http://pubs.rsc.org/en/content/articlepdf/2023/CB/D3CB00051F

Reference49 articles.

1. Current state of immunotherapy for glioblastoma

2. Tumor Cell Invasion in Glioblastoma

3. Cisplatin and Irinotecan as First-Line Chemotherapy for Previously Untreated Metastatic Thymic Carcinoma: Updated Analysis

4. Targeting Mitochondrial Oxidative Phosphorylation in Glioblastoma Therapy

5. Inhibition of mitochondrial translation suppresses glioblastoma stem cell growth

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