Antioxidant Response Activating nanoParticles (ARAPas) localize to atherosclerotic plaque and locally activate the Nrf2 pathway-Reference-Cited by-同舟云学术

Antioxidant Response Activating nanoParticles (ARAPas) localize to atherosclerotic plaque and locally activate the Nrf2 pathway

Published:2022 Issue:5 Volume:10 Page:1231-1247
ISSN:2047-4830
Container-title:Biomaterials Science
language:en
Short-container-title:Biomater. Sci.

Author:

Maiocchi Sophie¹²³⁴^ORCID,Cartaya Ana³⁴⁵^ORCID,Thai Sydney⁶,Akerman Adam⁶,Bahnson Edward¹²³⁴⁵^ORCID

Affiliation:

1. Department of Cell Biology and Physiology, University of North Carolina at Chapel Hill, NC 27599, USA

2. Curriculum of Toxicology and Environmental Medicine, University of North Carolina at Chapel Hill, NC 27599, USA

3. Center for Nanotechnology in Drug Delivery, University of North Carolina at Chapel Hill, NC 27599, USA

4. McAllister Heart Institute, University of North Carolina at Chapel Hill, NC 27599, USA

5. Department of Pharmacology, University of North Carolina at Chapel Hill, NC 27599, USA

6. Department of Surgery, University of North Carolina at Chapel Hill, NC 27599, USA

Abstract

Antioxidant Response Activating nanoParticles (ARAPas), but not un-targeted drug, induce protective genes in atherosclerotic plaque.

Funder

National Heart, Lung, and Blood Institute

National Cancer Institute

National Institute of Neurological Disorders and Stroke

National Institute of Child Health and Human Development

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

Link

http://pubs.rsc.org/en/content/articlepdf/2022/BM/D1BM01421H

Reference61 articles.

1. World Health Organization , Cardiovascular Diseases (CVDs) Fact Sheet , World Health Organization , 2021 , https://www.who.int/news-room/fact-sheets/detail/cardiovascular-diseases-(cvds)

2. Heart Disease and Stroke Statistics—2017 Update: A Report From the American Heart Association

3. Atherosclerosis

4. The immune system in atherosclerosis

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