A pre-formulation strategy for the liposome encapsulation of new thioctic acid conjugates for enhanced chemical stability and use as an efficient drug carrier for MPO-mediated atherosclerotic CVD treatment-Reference-Cited by-同舟云学术

A pre-formulation strategy for the liposome encapsulation of new thioctic acid conjugates for enhanced chemical stability and use as an efficient drug carrier for MPO-mediated atherosclerotic CVD treatment

Published:2020 Issue:7 Volume:44 Page:2755-2767
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Jayaraj Premkumar¹²³⁴⁵^ORCID,Shavi Gopal Venkatesh⁶⁷⁸,Srinivasan Ananda Kumar¹⁹¹⁰¹¹⁵^ORCID,Raghavendra Ramesh⁶⁷⁸,Sivaramakrishna Akella¹²³⁴⁵^ORCID,Desikan Rajagopal¹²³⁴⁵^ORCID

Affiliation:

1. Department of Chemistry

2. School of Advanced Sciences

3. Vellore Institute of Technology

4. Vellore

5. India

6. South Easter Applied Material Research Centre

7. Waterford Institute of Technology

8. Ireland

9. College of Engineering

10. Anna University

11. Chennai

Abstract

Lipoyl-apocynin and lipoyl-sesamol are bio-active conjugates of thioctic acid, synthesized using a benign chemical approachviathe combination of thioctic acid and the powerful bio-phytonutrients, apocynin and sesamol, respectively.

Funder

VIT University

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2020/NJ/C9NJ05258E

Reference64 articles.

1. Global cardiovascular risk assessment in the primary prevention of cardiovascular disease in adults: systematic review of systematic reviews

2. Liposome technology for cardiovascular disease treatment and diagnosis

3. Improving solubility and chemical stability of natural compounds for medicinal use by incorporation into liposomes

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