Inexpensive water soluble methyl methacrylate-functionalized hydroxyphthalimide: variations of the mycophenolic acid core for selective live cell imaging of free cysteine-Reference-Cited by-同舟云学术

Inexpensive water soluble methyl methacrylate-functionalized hydroxyphthalimide: variations of the mycophenolic acid core for selective live cell imaging of free cysteine

Published:2021 Issue:7 Volume:146 Page:2212-2220
ISSN:0003-2654
Container-title:The Analyst
language:en
Short-container-title:Analyst

Author:

Lee Woohyun¹²³⁴⁵,Yudhistira Tesla¹²³⁴⁵,Youn Wongu¹⁶⁷⁸⁵,Han Sol¹⁶⁷⁸⁵,Halle Mahesh B.¹²³⁴⁵,Choi Jae Hyuck¹²³⁴⁵,Kim Youngsam⁹¹⁰¹¹,Choi Insung S.¹⁶⁷⁸⁵^ORCID,Churchill David G.¹²³⁴⁵^ORCID

Affiliation:

1. Department of Chemistry

2. Molecular Logic Gate Laboratory

3. Korea Advanced Institute of Science and Technology (KAIST)

4. Daejeon 305-701

5. Republic of Korea

6. Center for Cell-Encapsulation Research

7. KAIST

8. Daejeon 34141

9. Korea Institute of Science and Technology (KIST)

10. 66123 Saarbrücken

11. Germany

Abstract

We report a new fluorescent probe (Myco-Cys) for live cell cysteine imaging. Myco-Cys contains a methacrylate cleavable pendant group that preferentially reacts with cysteine over homocysteine and glutathione to afford a “turn-on” response.

Funder

National Research Foundation of Korea

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/AN/D0AN02185G

Reference44 articles.

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