Rapid detection of Klebsiella pneumoniae producing extended spectrum β lactamase enzymes by infrared microspectroscopy and machine learning algorithms

Author:

Suleiman Manal12345,Abu-Aqil George12345,Sharaha Uraib12345,Riesenberg Klaris657,Sagi Orli8657,Lapidot Itshak91011127,Huleihel Mahmoud12345,Salman Ahmad1314157ORCID

Affiliation:

1. Department of Microbiology

2. Immunology and Genetics

3. Faculty of Health Sciences

4. Ben-Gurion University of the Negev

5. Beer-Sheva 84105

6. Soroka University Medical Center

7. Israel

8. Director of Microbiology Laboratory

9. Department of Electrical and Electronics Engineering

10. ACLP-Afeka Center for Language Processing

11. Afeka Tel-Aviv Academic College of Engineering

12. Tel-Aviv 69107

13. Department of Physics

14. SCE – Shamoon College of Engineering

15. Beer-Sheva 84100

Abstract

FTIR spectroscopy of Klebsiella pneumoniae in tandem with machine learning enables detection of ESBL producing isolates in 20 minutes after first culture, which helps physicians to treat bacterial infected patients appropriately.

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

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