One-step chemoselective conversion of tetrahydropyranyl ethers to silyl-protected alcohols-Reference-Cited by-同舟云学术

One-step chemoselective conversion of tetrahydropyranyl ethers to silyl-protected alcohols

Published:2014 Issue:28 Volume:4 Page:14475-14479
ISSN:2046-2069
Container-title:RSC Adv.
language:en
Short-container-title:RSC Adv.

Author:

Bergueiro Julián¹²³⁴,Montenegro Javier⁵³⁴,Saá Carlos⁵³⁴,López Susana¹²³⁴

Affiliation:

1. Departamento de Química Orgánica

2. Facultade de Química

3. Universidad de Santiago de Compostela

4. Santiago de Compostela, Spain

5. Centro Singular de Investigación en Química Biológica y Materiales Moleculares (CIQUS)

Abstract

A novel chemoselective one-pot transformation of acetals to silyl ethers is reported. Free hydroxyls, double bonds and triple bonds are unaffected in optimal reaction conditions. This practical, inexpensive protocol allows the selective replacement of acetal-forming protecting groups with silyl groups in a single step under mild conditions.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2014/RA/C4RA00655K

Reference34 articles.

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5. Symmetrical alkoxysilyl ethers. A new class of alcohol-protecting groups. Preparation of tert-butoxydiphenylsilyl ethers

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