Design and process study of chiral separation of (2S,4S)-1-(tert-butoxy carbonyl)-4-(methoxymethyl) pyrrolidine-2-carboxylic acid for green manufacturing-Reference-Cited by-同舟云学术

Design and process study of chiral separation of (2S,4S)-1-(tert-butoxy carbonyl)-4-(methoxymethyl) pyrrolidine-2-carboxylic acid for green manufacturing

Published:2024 Issue:5 Volume:26 Page:2673-2683
ISSN:1463-9262
Container-title:Green Chemistry
language:en
Short-container-title:Green Chem.

Author:

Ge Shuwang¹^ORCID,Fu Mingwei¹²,Gu Dihai¹,Wei Lai¹,Qian Kun³,Rui Qi²,Ma Yan²,Li Liang²,Wang Huaiqiu²,Li Lingchao⁴,Ge Min²,Wang Yihong¹^ORCID

Affiliation:

1. School of Chemistry and Chemical Engineering, Southeast University, Nanjing 211189, P. R. China

2. Nanjing Zenji Research Laboratories, Nanjing 211800, P. R. China

3. Shanghai institute of Materia Medica. Chinese Academy of Sciences, Shanghai 201203, P. R. China

4. Jiangsu Zenji Pharmaceuticals Ltd, Huaian 223100, P. R. China

Abstract

A novel scaled-up effective approach for chiral separation of (2S,4S)-1-(tert-butoxy carbonyl)-4-(methoxymethyl) pyrrolidine-2-carboxylic acid ((2S,4S)-TBMP) in water.

Funder

Priority Academic Program Development of Jiangsu Higher Education Institutions

Natural Science Foundation of Jiangsu Province

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/GC/D3GC04435A

Reference63 articles.

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5. The role of stereochemistry of antibiotic agents in the development of antibiotic resistance in the environment

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