Clickable gold-nanoparticles as generic probe precursors for facile photoaffinity labeling application
Author:
Affiliation:
1. Tokyo University of Agriculture and Technology
2. Department of Biotechnology and Life Science
3. Tokyo 184-8588
4. Japan
Abstract
Clickable photoreactive gold nanoparticles have been developed to facilitate one-step preparation of photoaffinity probes for bioactive small molecules and their application to target protein analysis.
Funder
Japan Society for the Promotion of Science
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2021/OB/D0OB01688H
Reference44 articles.
1. Development and Leading-Edge Application of Innovative Photoaffinity Labeling
2. Chemical proteomics approaches for identifying the cellular targets of natural products
3. The biological impact of mass-spectrometry-based proteomics
4. Target Identification for Small Bioactive Molecules: Finding the Needle in the Haystack
5. Affinity-based target identification for bioactive small molecules
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