Synthesis of 2-benzyl benzoxazoles and benzothiazoles via elemental sulfur promoted cyclization of styrenes with 2-nitrophenols and N,N-dialkyl-3-nitroanilines-Reference-Cited by-同舟云学术

Synthesis of 2-benzyl benzoxazoles and benzothiazoles via elemental sulfur promoted cyclization of styrenes with 2-nitrophenols and N,N-dialkyl-3-nitroanilines

Published:2024 Issue:6 Volume:22 Page:1234-1244
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Chau Truong K.¹²,Ho Nguyen T.¹²,Ho Tuan H.¹²^ORCID,Nguyen Anh T.¹²,Nguyen Khoa D.¹²,Phan Nam T. S.¹²^ORCID,Le Ha V.¹²,Nguyen Tung T.¹²^ORCID

Affiliation:

1. Faculty of Chemical Engineering, Ho Chi Minh City University of Technology (HCMUT), 268 Ly Thuong Kiet Street, District 10, Ho Chi Minh City, Vietnam

2. Vietnam National University Ho Chi Minh City, Linh Trung Ward, Ho Chi Minh City, Vietnam

Abstract

Annulation of 2-nitrophenols and N,N-dialkyl-3-nitroanilines with styrenes in the presence of elemental sulfur and the base DABCO successfully yielded 2-benzyl benzoxazoles and 2-benzyl benzothiazoles, respectively.

Funder

National Foundation for Science and Technology Development

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/OB/D3OB01775C

Reference35 articles.

1. Novel, potent aldose reductase inhibitors: 3,4-dihydro-4-oxo-3-[[5-(trifluoromethyl)-2-benzothiazolyl]methyl]-1-phthalazineacetic acid (zopolrestat) and congeners

2. Synthesis and structure–activity relationship of novel benzoxazole derivatives as melatonin receptor agonists

3. Synthesis, biological evaluation and 2D-QSAR analysis of benzoxazoles as antimicrobial agents

4. Recent Advances in the Development of Pharmacologically Active Compounds that Contain a Benzoxazole Scaffold

5. 1,3-Benzoxazole-4-carbonitrile as a novel antifungal scaffold of β-1,6-glucan synthesis inhibitors

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