Epigallocatechin gallate-zinc oxide co-crystalline nanoparticles as an anticancer drug that is non-toxic to normal cells-Reference-Cited by-同舟云学术

Epigallocatechin gallate-zinc oxide co-crystalline nanoparticles as an anticancer drug that is non-toxic to normal cells

Published:2018 Issue:14 Volume:8 Page:7369-7376
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Samutprasert Pawatsanai¹²³⁴⁵,Chiablaem Khajeelak⁶⁷⁸⁴,Teeraseranee Chanon⁹¹⁰³⁴,Phaiyarin Punnawich¹²³⁴,Pukfukdee Puttikorn¹²³⁴,Pienpinijtham Prompong¹²³⁴^ORCID,Svasti Jisnuson⁶⁷⁸⁴,Palaga Tanapat¹¹²³⁴¹²,Lirdprapamongkol Kriengsak⁶⁷⁸⁴,Wanichwecharungruang Supason¹²³⁴¹²^ORCID

Affiliation:

1. Department of Chemistry

2. Faculty of Science

3. Chulalongkorn University

4. Thailand

5. Center of Excellence on Petrochemical and Materials Technology

6. Laboratory of Biochemistry

7. Chulabhorn Research Institute

8. Bangkok 10210

9. Department of Nanoengineering

10. Faculty of Engineering

11. Department of Microbiology

12. Center of Excellence on Materials and Bio-interfaces

Abstract

A tea polyphenol, epigallocatechin-3-gallate (EGCG), can enhance cytotoxicity of Zinc in cancer cells. Here we synthesize hybrid EGCG-ZnO nanoparticles that can kill PC-3 prostate cancer cells at concentrations that are not toxic to normal cells.

Funder

Chulalongkorn University

Chulabhorn Research Institute

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/RA/C7RA10997K

Reference41 articles.

1. Evidence for operation of the direct zinc ligand exchange mechanism for trafficking, transport, and reactivity of zinc in mammalian cells

2. Metals in Neurobiology: Probing Their Chemistry and Biology with Molecular Imaging