Evaluation of a PSMA-targeted BNF nanoparticle construct

Author:

Behnam Azad Babak123,Banerjee Sangeeta R.123,Pullambhatla Mrudula123,Lacerda Silvia456,Foss Catherine A.123,Wang Yuchuan123,Ivkov Robert723,Pomper Martin G.12372

Affiliation:

1. Russell H. Morgan Department of Radiology and Radiological Science

2. Johns Hopkins Medical Institutions

3. Baltimore, USA

4. Centre for Biological Evaluation and Research

5. Food and Drug Administration

6. Bethesda, USA

7. Department of Radiation Oncology and Molecular Radiation Sciences

Abstract

A PSMA-targeted bionized nanoferrite (BNF) nanoparticle was developed and evaluated in an experimental model of prostate cancer showing prolonged circulation time and enhanced clearance from non-target sites.

Funder

National Institutes of Health

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

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