Vinylogous and stereoselective domino synthesis of pyrano[2,3-<i>c</i>]pyrroles from alkylidene meldrum's acids-Reference-Cited by-同舟云学术

Vinylogous and stereoselective domino synthesis of pyrano[2,3-c]pyrroles from alkylidene meldrum's acids

Published:2024 Issue:15 Volume:22 Page:2948-2952
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Savchuk Mariia¹,Vo-Thanh Giang²^ORCID,Oudeyer Sylvain¹^ORCID,Beucher Hélène¹^ORCID,Brière Jean-François¹^ORCID

Affiliation:

1. INSA Rouen Normandie, Univ Rouen Normandie, CNRS, Normandie Univ, COBRA UMR 6014, INC3M FR 3038, F-76000 Rouen, France

2. Institut de Chimie Moléculaire et des Matériaux d'Orsay. CNRS UMR 8182, Université Paris Saclay, 91405 Orsay Cedex, France

Abstract

An expeditious diatereoselective synthesis of pyrano[2,3-c]pyrroles thanks to a domino Vinylogous aza-Michael-Aldol-Cyclocondensation (aza-VMAC) reaction to alkylidene Meldrum's acid derivatives.

Funder

Université de Rouen

Institut National des Sciences Appliquées Rouen

Centre National de la Recherche Scientifique

European Regional Development Fund

Institut Carnot Santé Animale

Agence Nationale de la Recherche

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/OB/D4OB00233D

Reference33 articles.

1. Rings in Drugs

2. Analysis of the Structural Diversity, Substitution Patterns, and Frequency of Nitrogen Heterocycles among U.S. FDA Approved Pharmaceuticals

3. A synthetic antibiotic class overcoming bacterial multidrug resistance

4. Bicyclic Pyrrolidines for Medicinal Chemistry via [3 + 2]-Cycloaddition

5. Catalytic Asymmetric Inverse-Electron-Demand Hetero-Diels–Alder Reaction of Dioxopyrrolidines with Hetero-Substituted Alkenes