Cyto-friendly polymerization at cell surfaces modulates cell fate by clustering cell-surface receptors

Author:

Qi Jing12345,Li Weishuo12345,Xu Xiaoling12345,Jin Feiyang12345,Liu Di12345,Du Yan12345,Wang Jun12345,Ying Xiaoying12345,You Jian12345,Du Yongzhong12345ORCID,Ji Jiansong6785ORCID

Affiliation:

1. Institute of Pharmaceutics

2. College of Pharmaceutical Sciences

3. Zhejiang University

4. Hangzhou

5. China

6. Key Laboratory of Imaging Diagnosis and Minimally Invasive Intervention Research

7. Lishui Hospital of Zhejiang University

8. Lishui

Abstract

Cell-surface polymerization of anti-CD20 aptamer modified macromer to induce CD20 receptor clustering, and effectively initiate the apoptotic signals in cells.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Jiangsu Province

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

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