Pd-catalyzed desulfitative arylation for the synthesis of 2,5-diarylated oxazole-4-carboxylates using dioxygen as the terminal oxidant-Reference-Cited by-同舟云学术

Pd-catalyzed desulfitative arylation for the synthesis of 2,5-diarylated oxazole-4-carboxylates using dioxygen as the terminal oxidant

Published:2017 Issue:40 Volume:15 Page:8504-8507
ISSN:1477-0520
Container-title:Org. Biomol. Chem.
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Tang Xiaodong¹²³⁴⁵^ORCID,Yang Kai²⁶⁷⁵,Zeng Liying⁸³⁴⁵,Liu Qiang⁸³⁴⁵,Chen Huoji⁸³⁴⁵^ORCID

Affiliation:

1. Guangdong Provincial Key Laboratory of New Drug Screening

2. School of Pharmaceutical Sciences

3. Southern Medical University

4. Baiyun District

5. P. R. China

6. Gannan Medical University

7. Ganzhou

8. School of Traditional Chinese Medicine

Abstract

A novel palladium-catalyzed approach for constructing 2,5-diarylated oxazole-4-carboxylates using sodium arylsulfinates as the aryl source has been demonstrated.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/OB/C7OB01912B

Reference41 articles.

1. Recent advances in the total syntheses of oxazole-containing natural products

2. Synthesis of amino acids and related compounds. 29. Synthesis and hypolipidemic activities of 5-thienyl-4-oxazoleacetic acid derivatives

3. Synthesis and scintillating efficiencies of 4-functionalised-2,5-diphenyloxazoles

4. Covalent Incorporation of 2,5-Diphenyloxazole in Sol−Gel Matrices and Their Application in Radioanalytical Chemistry

5. Synthesis, evaluation and incorporation into liposomes of 4-functionalised-2,5-diphenyloxazole derivatives for application in scintillation proximity assays

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