Generalizable synthesis of bioresponsive near-infrared fluorescent probes: sulfonated heptamethine cyanine prototype for imaging cell hypoxia
Author:
Affiliation:
1. Department of Chemistry and Biochemistry
2. 251 Nieuwland Science Hall
3. University of Notre Dame
4. USA
Abstract
A new synthetic method produces a bioresponsive near-infrared molecular probe that undergoes “turn-on” fluorescence for microscopic imaging of hypoxia.
Funder
National Institute of General Medical Sciences
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2021/OB/D1OB00426C
Reference27 articles.
1. Cyanine Conjugate‐Based Biomedical Imaging Probes
2. Bioresponsive probes for molecular imaging: concepts andin vivoapplications
3. Activatable fluorescence: From small molecule to nanoparticle
4. Fluorescent Chemosensors as Future Tools for Cancer Biology
5. Approach to a Substituted Heptamethine Cyanine Chain by the Ring Opening of Zincke Salts
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